263 cruises leaving from San Diego, on 6 lines lasting 2 to 90 nights, from $229.
Departures
263
Fares From
$229
Trip Length
2 to 90 nights
Cruise Lines
6
On Sale Now
Disney Cruise Line
4 Nights • Disney Magic
Sep 21, 2026 • departs San Diego
Disney Cruise Line
3 Nights • Disney Magic
Sep 25, 2026 • departs San Diego
Disney Cruise Line
4 Nights • Disney Magic
Oct 1, 2026 • departs San Diego
Holland America Line
16 Nights • Nieuw Amsterdam
Oct 2, 2026 • departs San Diego
Royal Caribbean International
2 Nights • Serenade of the Seas
Oct 2, 2026 • departs San Diego
MSC Cruises
14 Nights • MSC Poesia
Oct 3, 2026 • departs San Diego
Disney Cruise Line
7 Nights • Disney Wonder
Oct 3, 2026 • departs San Diego
Royal Caribbean International
7 Nights • Serenade of the Seas
Oct 4, 2026 • departs San Diego
Holland America Line
7 Nights • Zaandam
Oct 8, 2026 • departs San Diego
Narrow It Down
Lines Sailing From Here
Where These Sailings Go
Where These Sailings Call
263 cruises currently leave from San Diego, on 6 lines lasting 2 to 90 nights, from $229.
Most are with Disney Cruise Line, Holland America Line and Royal Caribbean International. They are filed mainly under Mexico and Hawaii. An itinerary from San Diego usually also calls at Ensenada, Cabo San Lucas and Mazatlán.
Every sailing above is bookable through us. If you cannot see the week you want, ask and we can check availability and fares that are not on the page.
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