379 cruises calling at Natchez, on 1 lines lasting 6 to 22 nights, from $3,420.
Sailings Available
379
Fares From
$3,420
Trip Length
6 to 22 nights
On Sale Now
American Cruise Lines
15 Nights • American Serenade
Sep 25, 2026 • departs St. Paul
American Cruise Lines
8 Nights • American Heritage
Sep 25, 2026 • departs Memphis
American Cruise Lines
11 Nights • American Heritage
Oct 2, 2026 • departs New Orleans
American Cruise Lines
7 Nights • American Serenade
Oct 9, 2026 • departs New Orleans
American Cruise Lines
7 Nights • American Heritage
Oct 12, 2026 • departs New Orleans
American Cruise Lines
8 Nights • American Serenade
Oct 15, 2026 • departs Memphis
American Cruise Lines
15 Nights • American Melody
Oct 16, 2026 • departs St. Paul
American Cruise Lines
8 Nights • American Splendor
Oct 27, 2026 • departs Memphis
American Cruise Lines
11 Nights • American Serenade
Oct 29, 2026 • departs New Orleans
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Lines That Call Here
Where These Sailings Go
Often Paired With
379 cruises currently call at Natchez, on 1 lines lasting 6 to 22 nights, from $3,420.
Most are with American Cruise Lines. They are filed mainly under US Rivers. An itinerary calling at Natchez usually also calls at New Orleans, Vicksburg and Baton Rouge.
Every sailing above is bookable through us. If you cannot see the week you want, ask and we can check availability and fares that are not on the page.
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