American Cruise Lines
Highlights of the Mississippi Cruise
US Rivers
Sailing Itinerary
Trip Details
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Your Ship
American Serenade
The Mississippi end to end, from Memphis and St. Louis, and one of the three boats opening up the Arkansas
Aboard
- Sixth of the line's modern riverboats, and one of the three with the Sky Walk top deck
- 91 staterooms for 180 guests, all of them with private step-out balconies
- An eight-foot draft, shallow enough for the Arkansas River as far up as Tulsa
- Named best new river ship in Cruise Critic's 2023 Editors' Picks
- Memphis to New Orleans on the lower river most weeks, St. Louis to St. Paul on the upper
- A run up the Arkansas from Tulsa to Little Rock, on a river with no cruise history at all
Ashore
Where You Stop
US Rivers
America's Rivers
The Mississippi, the Columbia and the Snake aboard small ships that dock in the middle of town: no passport, no flight over an ocean, and a different American city every morning.
- Best Time to Go
- April to November, with fall color on the Mississippi in October
- Typical Length
- 7 to 15 nights
Compare Dates
The Same Trip, Other Weeks
The identical itinerary on this ship, priced by departure. Fares move week to week, and the difference is often larger than anything else on this page.
| Departs | Inside | Oceanview | Balcony | Suite | From |
|---|---|---|---|---|---|
| October 9, 2026This sailing | |||||
| February 13, 2027 | |||||
| October 28, 2027 | |||||
| November 3, 2027 |
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