American Cruise Lines
Upper Mississippi River Cruise
US Rivers
Sailing Itinerary
Trip Details
Speak With A Specialist
Ready to Book?
Our travel experts are standing by to help plan the perfect getaway. Call us, or send a note and we will come back to you.
Your Ship
American Serenade
The Mississippi end to end, from Memphis and St. Louis, and one of the three boats opening up the Arkansas
Aboard
- Sixth of the line's modern riverboats, and one of the three with the Sky Walk top deck
- 91 staterooms for 180 guests, all of them with private step-out balconies
- An eight-foot draft, shallow enough for the Arkansas River as far up as Tulsa
- Named best new river ship in Cruise Critic's 2023 Editors' Picks
- Memphis to New Orleans on the lower river most weeks, St. Louis to St. Paul on the upper
- A run up the Arkansas from Tulsa to Little Rock, on a river with no cruise history at all
US Rivers
America's Rivers
The Mississippi, the Columbia and the Snake aboard small ships that dock in the middle of town: no passport, no flight over an ocean, and a different American city every morning.
- Best Time to Go
- April to November, with fall color on the Mississippi in October
- Typical Length
- 7 to 15 nights
Compare Dates
The Same Trip, Other Weeks
The identical itinerary on this ship, priced by departure. Fares move week to week, and the difference is often larger than anything else on this page.
| Departs | Inside | Oceanview | Balcony | Suite | From |
|---|---|---|---|---|---|
| August 27, 2027 | |||||
| September 3, 2027 | |||||
| September 10, 2027 | |||||
| September 17, 2027 | |||||
| July 14, 2028 | |||||
| July 21, 2028 | |||||
| July 28, 2028 | |||||
| August 4, 2028 | |||||
| August 11, 2028This sailing | |||||
| August 18, 2028 | |||||
| July 6, 2029 | |||||
| July 13, 2029 | |||||
| July 20, 2029 |
Compare Alternatives
Sailing the Same Week
Other vacations of about the same length leaving within a few days of August 11, 2028, nearest departure ports first.
American Cruise Lines • 8 Nights
Columbia & Snake Rivers Cruise
American Encore
Aug 11, 2028 • departs Portland
American Cruise Lines • 8 Nights
Columbia & Snake Rivers Cruise
American Anthem
Aug 11, 2028 • departs Portland
American Cruise Lines • 8 Nights
Columbia & Snake Rivers Cruise
American Pride
Aug 9, 2028 • departs Portland
American Cruise Lines • 9 Nights
Ohio River Cruise
American Symphony
Aug 9, 2028 • departs Louisville
American Cruise Lines • 8 Nights
Columbia & Snake Rivers Cruise
American Jazz
Aug 13, 2028 • departs Portland
American Cruise Lines • 8 Nights
Columbia & Snake Rivers Cruise
American Harmony
Aug 8, 2028 • departs Portland