American Cruise Lines
Lower Mississippi River Cruise
US Rivers
Sailing Itinerary
Trip Details
Speak With A Specialist
Ready to Book?
Our travel experts are standing by to help plan the perfect getaway. Call us, or send a note and we will come back to you.
Your Ship
American Serenade
The Mississippi end to end, from Memphis and St. Louis, and one of the three boats opening up the Arkansas
Aboard
- Sixth of the line's modern riverboats, and one of the three with the Sky Walk top deck
- 91 staterooms for 180 guests, all of them with private step-out balconies
- An eight-foot draft, shallow enough for the Arkansas River as far up as Tulsa
- Named best new river ship in Cruise Critic's 2023 Editors' Picks
- Memphis to New Orleans on the lower river most weeks, St. Louis to St. Paul on the upper
- A run up the Arkansas from Tulsa to Little Rock, on a river with no cruise history at all
Ashore
Where You Stop
US Rivers
America's Rivers
The Mississippi, the Columbia and the Snake aboard small ships that dock in the middle of town: no passport, no flight over an ocean, and a different American city every morning.
- Best Time to Go
- April to November, with fall color on the Mississippi in October
- Typical Length
- 7 to 15 nights
Compare Dates
The Same Trip, Other Weeks
The identical itinerary on this ship, priced by departure. Fares move week to week, and the difference is often larger than anything else on this page.
| Departs | Inside | Oceanview | Balcony | Suite | From |
|---|---|---|---|---|---|
| November 9, 2027 | |||||
| November 16, 2027This sailing | |||||
| November 23, 2027 | |||||
| November 30, 2027 | |||||
| December 7, 2027 | |||||
| December 14, 2027 | |||||
| December 21, 2027 | |||||
| December 28, 2027 | |||||
| February 11, 2028 | |||||
| February 18, 2028 | |||||
| February 25, 2028 | |||||
| March 3, 2028 | |||||
| March 10, 2028 |
Compare Alternatives
Sailing the Same Week
Other vacations of about the same length leaving within a few days of November 16, 2027, nearest departure ports first.
American Cruise Lines • 8 Nights
Lower Mississippi River Cruise
American Melody
Nov 19, 2027 • departs Memphis
From
American Cruise Lines • 7 Nights
Highlights of the Mississippi Cruise
American Splendor
Nov 16, 2027 • departs New Orleans
From
American Cruise Lines • 8 Nights
Arkansas River Cruise
American Symphony
Nov 19, 2027 • departs Tulsa
From
AmaWaterways • 8 Nights
Secrets of Egypt & the Nile
AmaLilia
Nov 16, 2027 • departs Cairo
From
AmaWaterways • 7 Nights
Swiss Alps & Rhine Castles (Festive Delights)
AmaVenita
Nov 16, 2027 • departs Basel
From
AmaWaterways • 7 Nights
Rhine Castles & Swiss Alps (Festive Delights)
AmaSerena
Nov 16, 2027 • departs Amsterdam
From